Separation and enrichment of enantiopure from racemic compounds using magnetic levitation.

نویسندگان

  • Xiaochuan Yang
  • Shin Yee Wong
  • David K Bwambok
  • Manza B J Atkinson
  • Xi Zhang
  • George M Whitesides
  • Allan S Myerson
چکیده

Crystallization of a solution with high enantiomeric excess can generate a mixture of crystals of the desired enantiomer and the racemic compound. Using a mixture of S-/RS-ibuprofen crystals as a model, we demonstrated that magnetic levitation (MagLev) is a useful technique for analysis, separation and enantioenrichment of chiral/racemic products.

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عنوان ژورنال:
  • Chemical communications

دوره 50 56  شماره 

صفحات  -

تاریخ انتشار 2014